Ad-Aware and Spybot are probably the two most well known antispyware solutions. However, they frequently fail to catch the more crafty spyware. Here is a list of five solutions known to get rid of the problem when all others fail.
1. Webroot Spy Sweeper
http://www.deprice.com/webrootspysweeper.htm
PC Magazine's Best of the Year 2004 for antispyware, Spy Sweeper now scans for spyware 30% faster. Spy Sweeper detects and successfully removes vicious programs like CoolWebSearch. For advanced protection, Active Shields defend your browser and operating system from attempted spyware installations. Enhanced Internet Explorer shields block changes to your browser settings. Several operating system shields reinforce its ability to catch spyware when it attempts to download, install or run on a user's PC.
2. Spyware Doctor
http://www.deprice.com/spywaredoctor.htm
Spyware Doctor provides 3-way spyware protection through real-time threat blocking, scanning and immunization, anything less is like putting locks on the front door of your house but letting intruders in through the side or back door. This is one of the many reasons why the award-winning Spyware Doctor has been chosen by millions of users to protect their PCs against spyware, adware, trojans, keyloggers, spybots and tracking threats.
3.BitDefender
http://www.deprice.com/bitdefenderstandard.htm
Bitdefender Standard is a powerful antivirus tool with features that best meet your security needs. Ease of use and automatic updating make BitDefender Standard an "install and forget" antivirus product. Suspicious/infected files can optionally be backed up into a safe quarantine area before being disinfected or deleted. The contents of the quarantine can be sent to BitDefender Labs, for detailed analysis. Files that proved harmless can be easily moved out of quarantine, back to their original place.
4. X-Cleaner Deluxe
http://www.deprice.com/xcleanerdeluxe.htm
X-Cleaner is a top ranked privacy software solution from Xblock, one of the most trusted names in anti-spyware technology. X-Cleaner not only deletes browser and system usage tracks, shreds pictures and generates secure passwords it also features unique anti-spy and anti-adware technology and inoculation features that help prevent infections.
5. Geek Superhero
http://www.deprice.com/geeksuperhero.htm
Geek Superhero watches your computer for changes, immediately notifying you when a change is made to confirm you want to keep or reject the change. This saves you from lots of headaches. (A "Computer Setting Firewall" is an excellent description.) Geek Superhero protects your web browser's home page and other important settings. It lets you easily fix things if your browser has been taken over by a hijacker, and watches for hijackers trying to invade.
David Deprice regularly reviews antispyware solutions and makes his findings publically available at http://www.deprice.com/utilities.htm